Amantadine and/or transcranial magnetic stimulation for fatigue associated with multiple sclerosis (FETEM): study protocol for a phase 3 randomised, double-blind, cross-over, controlled clinical trial.

Jordi A Matias-GuiuJavier González-RosaMiguel Ángel HernándezMaria Luisa Martínez-GinésAntonio PortolésNatalia Pérez-MacíasJulián Benito-LeónIván PadrónJulio PrietoJorge Matias-Guiu

Published in: BMJ open (2024)

EudraCT 2021-004868-95; NCT05809414.

Keyphrases

transcranial magnetic stimulation
double blind
multiple sclerosis
clinical trial
high frequency
placebo controlled
phase ii
phase iii
open label
sleep quality
study protocol
white matter
depressive symptoms