Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis.
Lyda Z RojasMarija GlisicLaura Pletsch-BorbaLuis E EcheverríaWichor M BramerArjola BanoNajada StringaAsija ZaciragicBledar KrajaEralda AsllanajRajiv ChowdhuryCarlos A MorilloOscar L Rueda-OchoaOscar H FrancoTaulant MukaPublished in: PLoS neglected tropical diseases (2018)
This systematic review and meta-analysis provides an update and synthesis in this field. This research of observational studies indicates a significant excess in prevalence of ECG abnormalities (40.1%) related to T. cruzi infection in the general population from Chagas endemic regions, being the most common ventricular (RBBB and LAFB), and A-V B (first-degree) node conduction abnormalities as well as arrhythmias (AF or flutter and VE). Also, prevalence of ECG alterations in children was similar to that in adults and suggests earlier onset of cardiac disease.