The "Asthma-Polycystic Ovary Overlap Syndrome" and the Therapeutic Role of Myo-Inositol.
Gabriella GuarnieriMatteo IervolinoSara CavalloneVittorio UnferAndrea VianelloPublished in: International journal of molecular sciences (2023)
Asthma is a heterogeneous inflammatory disease characterized by abnormalities in immune response. Due to the inherent complexity of the disease and the presence of comorbidities, asthma control is often difficult to obtain. In asthmatic patients, an increased prevalence of irregular menstrual cycles, infertility, obesity, and insulin resistance has been reported. Given that these conditions are also common in patients with polycystic ovary syndrome (PCOS), we propose the definition of "asthma-PCOS overlap syndrome" to indicate a medical condition which shares characteristics of both diseases. The aim of this review is to analyze the links between asthma and PCOS and evaluate the therapeutic role of myo-inositol, a natural compound currently utilized in patients with PCOS, in the management of asthma patients.
Keyphrases
- end stage renal disease
- chronic obstructive pulmonary disease
- lung function
- insulin resistance
- chronic kidney disease
- ejection fraction
- newly diagnosed
- immune response
- prognostic factors
- metabolic syndrome
- peritoneal dialysis
- adipose tissue
- oxidative stress
- patient reported outcomes
- allergic rhinitis
- case report
- high fat diet