Polycystic ovary syndrome: associations with cardiovascular disease.
Jamie L BenhamA GoldbergH TeedeC T TayPublished in: Climacteric : the journal of the International Menopause Society (2023)
Polycystic ovary syndrome (PCOS), characterized by abnormal menstrual periods, elevated androgen levels and polycystic ovary morphology on ultrasound, is the most common endocrine disorder among females. PCOS is associated with cardiovascular disease (CVD) risk factors including diabetes, obesity, metabolic syndrome, adverse pregnancy outcomes such as pre-eclampsia and psychosocial distress including depression. Previous evidence on the association between PCOS and CVD is inconclusive but the latest 2023 International Evidence-Based PCOS Guideline identifies PCOS as a risk factor for CVD. This review will discuss the relationship between PCOS and CVD along with current direction for CVD screening and prevention among individuals with PCOS.
Keyphrases
- polycystic ovary syndrome
- insulin resistance
- cardiovascular disease
- metabolic syndrome
- type diabetes
- pregnancy outcomes
- risk factors
- skeletal muscle
- magnetic resonance imaging
- pregnant women
- glycemic control
- cardiovascular events
- uric acid
- dna methylation
- computed tomography
- coronary artery disease
- ultrasound guided