Lack of Smoking Effects on Pharmacokinetics of Oral Paliperidone-analysis of a Naturalistic Therapeutic Drug Monitoring Sample.
Georgios SchoretsanitisEkkerhard HaenAndreas ConcaDaria PiacentinoFlorian RiddersChristoph HiemkeGerhard GründerMichael PaulzenPublished in: Pharmacopsychiatry (2020)
Paliperidone is not affected by smoking, and paliperidone dose-adjustments in smokers may not be necessary. This may be seen as an essential difference to risperidone, whose cytochrome-mediated metabolism might be affected by smoking.
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