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[Analysis of the phenotypic heterogeneity of CD123-positive cells in Kikuchi-Fujimoto disease using a sequential immunoperoxidase labeling and erasing method].

I N SpiridonovZ P AsaulenkoYu A Krivolapov
Published in: Arkhiv patologii (2021)
SIMPLE has shown the phenotypic heterogeneity of CD123-positive cells (some of them may be PDCs) and could identify 4 immunophenotypically distinct subpopulations in the affected lymph nodes in patients with KFD. Further investigations are needed to define the role of subpopulations in the pathogenesis of KFD and other diseases.
Keyphrases
  • induced apoptosis
  • lymph node
  • cell cycle arrest
  • single cell
  • endoplasmic reticulum stress
  • signaling pathway
  • early stage
  • nk cells