Water-soluble Yb 3+ , Er 3+ codoped NaYF 4 nanoparticles induced SGC-7901 cell apoptosis through mitochondrial dysfunction and ROS-mediated ER stress.

Chen LiuShaoqiang SunJingwei Mao

Published in: Human & experimental toxicology (2023)

UCNP induced SGC-7901 cell apoptosis by promoting mitochondrial dysfunction and ROS-mediated endoplasmic reticulum (ER) stress, initiating the caspase-9/caspase-3 cascade.

Keyphrases

endoplasmic reticulum
cell death
water soluble
high glucose
diabetic rats
cell proliferation
dna damage
reactive oxygen species
induced apoptosis
drug induced
oxidative stress
endothelial cells
signaling pathway