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Genetic Risk Score Enhances Coronary Artery Disease Risk Prediction in Individuals With Type 1 Diabetes.

Raija LithoviusAnni A AntikainenStefan MutterErkka ValoCarol ForsblomJoanne B ColeErkka ValoPer-Henrik Groop
Published in: Diabetes care (2022)
A GRS identified individuals at high risk of CAD and worked better in younger individuals. GRS was also an independent risk factor for CAD, with a predictive power comparable to that of HbA1c and HDL and total cholesterol, and when incorporated into a clinical model, modestly improved the predictions. The GRS promises early risk stratification in clinical practice by enhancing the prediction of CAD.
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