Is short-term antidepressant treatment effective and safe in bipolar depression? Results from an observational multicenter study.

Antonio TundoLaura Musetti Claudia Del Grande Rocco de FilippisLuca ProiettiErika CambialiCaterina FranceschiniLiliana Dell'Osso

Published in: Human psychopharmacology (2020)

Acute AD treatment of bipolar depression is effective in the short-term and safe in the short- and long-term, when administered in combination with MSs and/or second-generation antipsychotics, with a low risk of switch, mixed depression and cycle acceleration.

Keyphrases

depressive symptoms
sleep quality
bipolar disorder
combination therapy
respiratory failure
replacement therapy