Amiodarone accumulates two cholesterol precursors in myocardium: A controlled clinical study.

Amiodarone treatment caused the accumulation of desmosterol and zymostenol in myocardium In particular, myocardial desmosterol concentrations were substantially elevated, which may play a part in some of the therapeutic and adverse effects of amiodarone treatment. This article is protected by copyright. All rights reserved.