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Comparing rare variants versus common in the pathogenesis of nonalcoholic fatty liver disease: a whole exome sequencing approach.

Govardhan BaleAnand V KulkarniNagaraja Rao PadakiP Balachandran MenonSundeep LakhtakiaSowmya IyengarAnuradha SekaranSmita C PawarNageshwar Reddy DuvvurRavikanth Venkata Vishnubhotla
Published in: Journal of gastroenterology and hepatology (2023)
Elucidating the contribution of rare pathogenic variants would enhance our understanding of the pathogenesis. Including the rarer genes in the polygenic risk scores would enhance prediction power.
Keyphrases
  • copy number
  • genome wide
  • transcription factor