Investigation of Copaifera genus as a new source of antimycobaterial agents.
Jéssica Aparecida AlvesFariza AbrãoThaís da Silva MoraesJaqueline Lopes DamascenoMarcos Fernando Dos Santos MoraesRodrigo Cassio Sola VenezianiSérgio Ricardo AmbrósioA N D Jairo Kenupp BastosMayker Lazaro Dantas MirandaCarlos Henrique Martins da SilvaPublished in: Future science OA (2020)
Among the assayed oleoresins and plant extracts, the Copaifera langsdorffii, Copaifera duckei, Copaifera reticulata and Copaifera trapezifolia oleoresins provided the lowest MIC values against some of the tested strains. The combination of Copaifera spp. samples with isoniazid did not evidence any synergistic action. Some Copaifera spp. oleoresins may represent a future source for the discovery of new antimycobacterial drugs due to their low MIC values.