Real World Performance of The Afirma Genomic Sequencing Classifier (GSC) - A Meta-analysis.
Christian E NasrMassimiliano AndrioliMayumi EndoR Mack HarrellMasha J LivhitsIbitoro OsakwePreethi PolavarapuAllan SipersteinShuanzeng WeiXingyu ZhengRuochen JiangYangyang HaoJIng HuangJoshua P KlopperRichard T KloosGiulia KennedyTrevor E AngellPublished in: The Journal of clinical endocrinology and metabolism (2022)
RW data for the Afirma GSC demonstrates significantly better oSP and oPPV performance compared to the VS, indicating an increased yield of cancers for resected GSC suspicious nodules. The higher BCR likely increases the overall rate of clinical observation in lieu of surgery.