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Isolation and Characterization of Six Novel Fusobacterium necrophorum Phages.

Cory SchwarzJacques MathieuJenny Laverde GomezMegan R MillerMarina TikhonovaClark HamorPedro J J Alvarez
Published in: PHAGE (New Rochelle, N.Y.) (2024)
Although all phages isolated contained sequences bearing similarities to genes implicated in lysogeny, the four selected for use in cocktails showed potential in inhibiting host growth, with several demonstrating promising attributes for biocontrol and therapeutic applications. Phage cocktails that may offer enhanced antibacterial activity were also identified, indicating the potential of some lysogenic phages to be adapted for biocontrol or therapeutic purposes when lytic phages are difficult to obtain.
Keyphrases
  • pseudomonas aeruginosa
  • signaling pathway
  • genome wide
  • human health
  • gene expression
  • cystic fibrosis
  • transcription factor