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Epicardial Adipose Tissue Changes After Bariatric and Metabolic Surgery: a Systematic Review and Meta-analysis.

Juan Pablo Scarano PereiraMatteo CalafattiAlessandro MartininoDharmanand RamnarainChristine StierChetan ParmarSylvia WeinerLukas R DekkerTill HasenbergOlga WolfSjaak Pouwels
Published in: Obesity surgery (2023)
Epicardial adipose tissue (EAT) is a visceral fat depot located between the myocardium and visceral epicardium. Emerging evidence suggests that excessive EAT is linked to increased risk of cardiovascular conditions and other metabolic diseases. A literature search was conducted from the earliest studies to the 26th of November 2022 on PubMed, Embase, and the Cochrane. All the studies evaluating changes in EAT, pericardial adipose tissue (PAT), or total cardiac fat loss before and after BS were included. From 623 articles, 35 were eventually included in the systematic review. Twenty-one studies showed a significant reduction of EAT after BS, and only one study showed a non-significant reduction (p = 0.2).
Keyphrases
  • adipose tissue
  • insulin resistance
  • systematic review
  • high fat diet
  • case control
  • minimally invasive
  • heart failure
  • type diabetes
  • left ventricular
  • body mass index
  • weight gain
  • skeletal muscle