Thrombin cleaves IL-33 and modulates IL-33-activated allergic lung inflammation.

Yuying HuangXuezhen LiLin ZhuChunrong HuangWen ChenZhiyang LingSongLing ZhuXintong FengChunyan YiWangpeng GuChenghua YanJing WangLiyan MaXiao SuRanran DaiGuochao ShiBing SunYaguang Zhang

Published in: Allergy (2022)

The data suggested that thrombin inhibitors administration could be effective in treating lung inflammation by regulating ILC2s via IL-33 maturation, indicating that targeting thrombin is a potential way to treat allergic diseases.

Keyphrases

oxidative stress
electronic health record
risk assessment
deep learning
nk cells