SYN1 overexpression improves cognitive function and promotes the release of various neurotransmitters in AD rats by inhibiting oxidative stress and inflammatory responses through cAMP signaling pathway activation. These findings may provide a theoretical basis for the targeted diagnosis and treatment of AD.
Keyphrases
- cognitive impairment
- signaling pathway
- oxidative stress
- induced apoptosis
- epithelial mesenchymal transition
- pi k akt
- traumatic brain injury
- transcription factor
- cognitive decline
- mouse model
- lps induced
- ischemia reperfusion injury
- binding protein
- inflammatory response
- drug delivery
- blood brain barrier
- protein kinase
- brain injury