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Glucose-6-phosphate dehydrogenase deficiency is more prevalent in Duffy-null red blood cell transfusion in sickle cell disease.

Marianne E McPherson YeeRichard O FrancisNaomi L C LubanKirk A EasleyChristopher M LoughJohn D RobackCassandra D JosephsonRoss M Fasano
Published in: Transfusion (2022)
Selection of Duffy-null RBC units may result in shorter in vivo survival of transfused RBCs due to a higher likelihood of transfusing units from G6PD deficient donors.
Keyphrases
  • red blood cell
  • sickle cell disease
  • blood glucose
  • free survival
  • replacement therapy
  • adipose tissue
  • acute kidney injury
  • skeletal muscle
  • insulin resistance
  • wild type