Diagnostic Dilemma of ANA-negative Pediatric Systemic Lupus Erythematosus in a South Asian Female.

Qaisar Ali KhanTehmina KhanParsa AbdiChristopher FarkouhMichelle AnthonyFaiza Amatul HadiSumaira Iram

Published in: Clinical medicine insights. Case reports (2023)

ANA positivity is an entry criterion for SLE; rarely, cases of ANA-negative SLE may present. A typical clinical presentation may help determine the diagnosis in such a scenario. However, still, the physician should rule out immunodeficiency and other systemic illnesses before reaching a diagnosis of ANA-negative pediatric SLE.

Keyphrases

systemic lupus erythematosus
disease activity
primary care
emergency department