Abolishing spontaneous epileptiform activity in human brain tissue through AMPA receptor inhibition.
Sukhvir K WrightMax A WilsonRichard WalshWilliam B LoNilesh MundilShakti AgrawalSunny PhilipStefano SeriStuart D GreenhillGavin L WoodhallPublished in: Annals of clinical and translational neurology (2020)
This study confirms AMPAR antagonists inhibit epileptiform discharges in brain tissue resected in a wide range of pediatric epilepsies.