Abscisic acid stimulates the release of insulin and of GLP-1 in the rat perfused pancreas and intestine.

Valeria BoozCharlotte Bayer ChristiansenRune Ehrenreich KuhreMonika Yosifova SaltielGiovanna SocialiNicola SchaltenbergAlexander W FischerJörg HeerenElena ZocchiJens J HolstSantina Bruzzone

Published in: Diabetes/metabolism research and reviews (2018)

Our results indicate the existence of a cross talk between GLP-1 and ABA, whereby ABA stimulates GLP-1 secretion, and vice versa. Release of ABA could be considered as a new promising molecule in the strategy of type 2 diabetes treatment and as a new endogenous hormone in the regulation of glycaemia.

Keyphrases

transcription factor
arabidopsis thaliana
type diabetes
oxidative stress
metabolic syndrome
insulin resistance