Impact of the inversion time on regional brain perfusion estimation with clinical arterial spin labeling protocols.
Francesco SanvitoFulvia PalesiElisa RognoneLeonardo BarzaghiLudovica PascaGiancarlo GermaniValentina De GiorgisRenato BorgattiClaudia A M Gandini Wheeler-KingshottAnna PichiecchioPublished in: Magma (New York, N.Y.) (2021)
TI influences ASL perfusion estimates with a region-dependent effect. The presence of intraluminal arterial signal in PTAs and the longer arterial transit time in the DTAs (including watershed areas) may account for the TI-dependent differences. Watershed areas exhibiting a lower perfusion signal at short TIs (~ 1500 ms) should not be misinterpreted as focal hypoperfused areas.