Perineural invasion predicts for locoregional failure in patients with oesophageal adenocarcinoma treated with neoadjuvant chemoradiotherapy.
Ankur K PatelXueliang PanDiana M VilaWendy L FrankelWei ChenKyle A PerryRobert E MerrittDesmond M D'SouzaEvan J WuthrickTerence M WilliamsPublished in: Journal of clinical pathology (2020)
For patients with EAC treated with nCRT, PNI found at the time of surgery is significantly associated with worse LRFS. Our data support attempts to validate this finding and perhaps testing the role of adjuvant therapy in patients with PNI.