Evaluation of interstitial fibrosis in chronic kidney disease by multiparametric functional MRI and histopathologic analysis.

Wei MaoXiaoqiang DingYuqin DingBohong CaoCaixia FuBernd KuehnThomas BenkertRobert GrimmDominik NickelJianjun ZhouMengsu Zeng

Published in: European radiology (2022)

• In CKD patients, the renal cortical ADC value decreased and T1 value increased significantly compared with healthy volunteers. • Functional MRI revealed significantly decreased renal perfusion in CKD patients compared with healthy volunteers. • The renal cortical ADC, f, RBF, and T1 values were strongly correlated with the interstitial fibrosis of CKD.

Keyphrases

end stage renal disease
chronic kidney disease
newly diagnosed
ejection fraction
magnetic resonance imaging
prognostic factors
peritoneal dialysis
single cell
patient reported