Night-time gastric acid suppression by tegoprazan compared to vonoprazan or esomeprazole.

Eunsol YangSeokuee KimBongtae KimBoram KimYechan KimSung Sup ParkGeun Seog SongKyung-Sang YuIn-Jin JangSeungHwan Lee

Published in: British journal of clinical pharmacology (2022)

Tegoprazan produced more rapid, potent and well sustained night-time acid suppression vs. vonoprazan or esomeprazole when administered at night. Furthermore, tegoprazan showed no CYP2C19 phenotype dependency in acid suppression. It suggests the potential of tegoprazan, especially in preventing nocturnal acid breakthrough.

Keyphrases

helicobacter pylori
depressive symptoms
endoscopic submucosal dissection
loop mediated isothermal amplification