Western influenced lifestyle and Kv2.1 association as predicted biomarkers for Tunisian colorectal cancer.

Mouadh BarbirouHenok G WolduIkram SghaierSinda A BedouiAmina MokraniRadhia AamiAmel MezliniBesma Yacoubi-LoueslatiPeter J TonellatoBalkiss Bouhaouala-Zahar

Published in: BMC cancer (2020)

The risk of CRC increases with modifiable factors by Western influences on Tunisian lifestyle such as alcohol use, high fat consumption and possibly inadequate intake of vegetables. In addition, KCNB1 polymorphisms also markedly influence CRC susceptibility. Our study establishes key elements of a baseline characterization of clinical state, Western influenced lifestyle and KCNB1 variants associated with Tunisian CRC.

Keyphrases

metabolic syndrome
south africa
weight loss
physical activity
cardiovascular disease
copy number
type diabetes
magnetic resonance imaging
gene expression
body mass index
computed tomography
climate change