Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice.

Zixuan YiBei YangFangyu WanJing LuDongyang LiuLin LinYing XuZhikang CenMengqi FanWei LiuQiuhan LuGuozhi JiangYuying ZhangErfei SongJie GaoDewei Ye

Published in: Journal of ethnopharmacology (2024)

Our data demonstrated that the LGZG formula protected against DKD in mice and was closely associated with its inhibitory effects on PR3-mediated podocyte apoptosis.

Keyphrases

oxidative stress
endoplasmic reticulum stress
cell cycle arrest
high fat diet induced
cell death
diabetic nephropathy
human milk
type diabetes
high glucose
electronic health record
metabolic syndrome
insulin resistance
adipose tissue
artificial intelligence