Anti-Angiogenic Tyrosine Kinase Inhibitor-Related Toxicities Among Cancer Patients: A Systematic Review and Meta-Analysis.

Tai Van NguyenDiaddin HamdanGéraldine FalgaroneKien Hung DoQuang Van LeFrédéric PamoukdjianGuilhem Bousquet

Published in: Targeted oncology (2024)

This meta-analysis highlights the toxicity profiles of anti-angiogenic TKI monotherapies, and thus enables high-level recommendations for the choice of anti-angiogenic TKIs on the basis of the patient's age, ethnicity, comorbidities, and comedications, for personalized treatment.

Keyphrases

systematic review
oxidative stress
case report
tyrosine kinase
clinical practice
advanced non small cell lung cancer
epidermal growth factor receptor
replacement therapy