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Liposomal irinotecan with fluorouracil and leucovorin after gemcitabine-based therapy in Japanese patients with metastatic pancreatic cancer: additional safety analysis of a randomized phase 2 trial.

Junji FuruseMakoto UenoMasafumi IkedaTakuji OkusakaZhaoyang TengMomoko FuruyaTatsuya Ioka
Published in: Japanese journal of clinical oncology (2022)
We explored safety profile of nal-IRI combination regimen recognized as effective and tolerable treatment for Japanese unresectable pancreatic cancer patients. Although the treatment-emergent adverse events occurred were controllable, patients with prolonged toxicities should be closely managed.
Keyphrases
  • stem cells
  • locally advanced
  • radiation therapy
  • combination therapy
  • bone marrow
  • mesenchymal stem cells
  • rectal cancer
  • smoking cessation