Responders and nonresponders to topical capsaicin display distinct temporal summation of pain profiles.
Felyx WongAditi ReddyYeanuk RhoJan VollertPaul H StruttonSam W HughesPublished in: Pain reports (2023)
These data suggest that responders and nonresponders have different facilitatory pain mechanisms. The assessment of TSP may help to identify participants with stronger endogenous pain facilitation who may be more likely to respond to topical capsaicin.