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Guidelines for correlation coefficient threshold settings in metabolite correlation networks exemplified on a potato association panel.

David ToubianaHelena Maruenda
Published in: BMC bioinformatics (2021)
Our analysis corrected the previously stated Pearson's correlation coefficient threshold from 0.4 to 0.41 in the water recovery network and from 0.4 to 0.23 for the normal irrigation network. Furthermore, the proposed method suggested a correlation threshold of 0.84 for both mice networks rather than a threshold of 0.7 as applied earlier. We demonstrate that the proposed approach is a valuable tool for constructing biological meaningful networks.
Keyphrases
  • type diabetes
  • magnetic resonance imaging
  • computed tomography
  • skeletal muscle