Diazepam blocks 50 kHz ultrasonic vocalizations and stereotypies but not the increase in locomotor activity induced in rats by amphetamine.

Gisele de Oliveira GuaitaDebora Dalla VecchiaRoberto AndreatiniDonita L RobinsonRainer K W SchwartingClaudio Da Cunha

Published in: Psychopharmacology (2018)

These results suggest that diazepam blocks the rewarding effect of amphetamine. This finding is promising for basic research regarding treatments of substance use disorders and evaluation of the impact of benzodiazepines on motivation.

Keyphrases

high glucose
spinal cord injury
high frequency
diabetic rats
drug induced
oxidative stress