RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction.

Daichi EnomotoKotaro MatsumotoTomomi YamashitaArisa KobayashiMakiko MaedaHiroyuki NakayamaMasanori ObanaYasushi Fujio

Published in: PloS one (2017)

Heterozygous deletion of RORγt gene resulted in aggravated cardiac remodeling, accompanied by reduced capillary density, after MI, suggesting that RORγt-expressing cells contribute to tissue repair in infarcted myocardium.

Keyphrases

induced apoptosis
cell cycle arrest
left ventricular
endoplasmic reticulum stress
oxidative stress
cell death
gene expression
signaling pathway
copy number
transcription factor
cell proliferation
atrial fibrillation
pi k akt