Neurofilament light chain level in plasma extracellular vesicles and Parkinson's disease.

Chen-Chih ChungLung ChanJia-Hung ChenOluwaseun Adebayo BamoduChien-Tai Hong

Published in: Therapeutic advances in neurological disorders (2020)

Plasma EV NfL levels did not distinguish patients with PD from the neurological control group. The possible correlation between plasma EV NfL with the severity of motor symptoms within the PD patients, especially with akinetic rigidity, was noted. Further clinical validation of the blood EV NfL by a longitudinal follow-up study of PD patients is warranted.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
peritoneal dialysis
prognostic factors
patient reported outcomes