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Intense orthodontic force induces the three dental pulp nitric oxide synthase isoforms and leads to orofacial discomfort in rats.

José Edson Moreira SobrinhoMaria Thaynara AguiarLarissa Carvalho MachadoAnna Clara Aragão Matos CarlosAna Paula Negreiros Nunes AlvesKarine Cestaro MesquitaGeorge Táccio de Miranda CandeiroPaulo Goberlânio de Barros Silva
Published in: Orthodontics & craniofacial research (2022)
Thus, IDM induced inflammatory changes in the dental pulp reflecting in force-dependent pain/suffering signs.
Keyphrases
  • nitric oxide synthase
  • nitric oxide
  • single molecule
  • chronic pain
  • high glucose
  • diabetic rats
  • oxidative stress
  • pain management
  • neuropathic pain
  • drug induced
  • oral health
  • endothelial cells
  • spinal cord injury