The plasma metabolome of women in early pregnancy differs from that of non-pregnant women.
Samuel K HandelmanRoberto RomeroAdi Laurentiu TarcaPercy PacoraBrian IngramEli MaymonTinnakorn ChaiworapongsaSonia S HassanOffer ErezPublished in: PloS one (2019)
This high-throughput mass spectrometry study identified: 1) differences between pregnant vs. non-pregnant women in the abundance of 44% of the profiled plasma metabolites, including known and novel molecules and pathways; and 2) specific metabolites that changed with gestational age.
Keyphrases
- pregnant women
- gestational age
- pregnancy outcomes
- high throughput
- mass spectrometry
- ms ms
- birth weight
- preterm birth
- polycystic ovary syndrome
- single cell
- high resolution
- type diabetes
- capillary electrophoresis
- high performance liquid chromatography
- antibiotic resistance genes
- cervical cancer screening
- wastewater treatment
- solid phase extraction