The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke.
Nicholas W MuiAnaz UddinMichael P FortunatoBridget E NolanKevin M ClareAiden K LuiMohammed Al-JubooriChirag D GandhiFawaz Al-MuftiPublished in: Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences (2023)
IBD patients develop AIS at a younger age with similar rates of stroke severity to their non-IBD counterparts, but receive higher rates of tissue plasminogen activator administration and decreased rates of mechanical thrombectomy. Our research shows that patients with IBD are at risk for AIS at an earlier age and are more likely to have complications. This underlies a connection between IBD and a hypercoagulable state that could predispose patients to AIS.