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Anticholinergic Activity of Psychotropic Drugs and Cognitive Impairment Among Participants Aged 45 and Over: The CONSTANCES Study.

Abdelkrim ZiadClaudine BerrFabrice RuizBernard BégaudCédric LemogneMarcel GoldbergMarie ZinsThibault Mura
Published in: Drug safety (2021)
Our results suggest there is no clinically relevant association between the anticholinergic activity of antidepressant and anxiolytic drugs and cognitive impairment in middle-aged adults. An association could exist between AC+ antipsychotics and executive function.
Keyphrases
  • cognitive impairment
  • middle aged
  • major depressive disorder