Performance of diagnostic and predictive host blood transcriptomic signatures for Tuberculosis disease: A systematic review and meta-analysis.
Humphrey MulengaChambrez-Zita ZauchenbergerErick W BunyasiStanley Kimbung MbandiSimon C MendelsohnBenjamin KaginaAdam Penn-NicholsonThomas J ScribaMark HatherillPublished in: PloS one (2020)
Host blood mRNA signatures hold promise as triage tests for TB. Further optimisation is needed if mRNA signatures are to be used as standalone diagnostic or predictive tests for therapeutic decision-making.