Antibiotic treatment duration for bloodstream infections in critically ill children-A survey of pediatric infectious diseases and critical care clinicians for clinical equipoise.
Sandra PongRobert A FowlerSrinivas MurthyJeffrey M PernicaElaine GilfoylePatricia FontelaNicholas MitsakakisAsha C BowenWinnie SetoMichelle ScienceJames S HutchisonPhilippe A JouvetAsgar RishuNick DanemanPublished in: PloS one (2022)
The majority of clinicians currently recommend at least 10 days of antibiotics for most scenarios of bloodstream infections in critically ill children. There is practice heterogeneity in self-reported treatment duration recommendations among clinicians. Treatment durations were similar across different infectious syndromes. Under appropriate clinical conditions, most clinicians would be willing to enrol patients into a trial of shorter versus longer treatment for common syndromes associated with bloodstream infections.