Transcriptional Factors and Epigenetic Mechanisms in Obesity and Related Metabolic Comorbidities.

Published in: Cells (2022)

Recent advances in the study of chromatin remodeling and transcriptional machinery complex dysfunction, and how they drive metabolic-related gene expression have considerably increased our understanding of several molecular processes underlaying obesity and its complications [...].

Keyphrases

gene expression
insulin resistance
dna methylation
metabolic syndrome
transcription factor
weight loss
type diabetes
high fat diet induced
weight gain
dna damage
genome wide
risk factors
body mass index
oxidative stress
adipose tissue
single molecule
heat shock protein