Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway.
Qingyun TanWenming DongQingdong WangLi Gao
Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2024)
Dex was found to attenuate H/R-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway. Thus, this study might shed new lights on exploring new strategies for the treatment of MIRI.