Prediction of C-reactive protein dynamics during meropenem treatment in neonates and infants.

Hiie SoeorgHelgi PadariMari-Liis IlmojaKoit HerodesKarin KipperIrja LutsarTuuli Metsvahtnull null

Published in: British journal of clinical pharmacology (2023)

The developed PKPD model of meropenem and CRP as a function of meropenem cumulative AUC incorporating several patient characteristics predicts CRP dynamics with an error of <0.2 in most neonates/infants.

Keyphrases

gram negative
low birth weight
case report
multidrug resistant
combination therapy
replacement therapy