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Prediction of C-reactive protein dynamics during meropenem treatment in neonates and infants.

Hiie SoeorgHelgi PadariMari-Liis IlmojaKoit HerodesKarin KipperIrja LutsarTuuli Metsvahtnull null
Published in: British journal of clinical pharmacology (2023)
The developed PKPD model of meropenem and CRP as a function of meropenem cumulative AUC incorporating several patient characteristics predicts CRP dynamics with an error of <0.2 in most neonates/infants.
Keyphrases
  • gram negative
  • low birth weight
  • case report
  • multidrug resistant
  • combination therapy
  • replacement therapy