Prediction of C-reactive protein dynamics during meropenem treatment in neonates and infants.
Hiie SoeorgHelgi PadariMari-Liis IlmojaKoit HerodesKarin KipperIrja LutsarTuuli Metsvahtnull nullPublished in: British journal of clinical pharmacology (2023)
The developed PKPD model of meropenem and CRP as a function of meropenem cumulative AUC incorporating several patient characteristics predicts CRP dynamics with an error of <0.2 in most neonates/infants.