Genetic variation in the body mass index of adult survivors of childhood acute lymphoblastic leukemia: A report from the Childhood Cancer Survivor Study and the St. Jude Lifetime Cohort.
Melissa A RichardAustin L BrownJohn W BelmontMichael E ScheurerVidal M ArroyoKayla L FosterKathleen D KernMelissa M HudsonWendy M LeisenringM Fatih OkcuYadav SapkotaYutaka YasuiLindsay M MortonStephen J ChanockLeslie L RobisonGregory T ArmstrongSmita BhatiaKevin C OeffingerPhilip J LupoKala Y KamdarPublished in: Cancer (2020)
Adult survivors of childhood ALL have genetic heritability for BMI similar to that observed in the general population. This study provides evidence that treatment with CRT can modify the effect of genetic variants on adult BMI in childhood ALL survivors.