Role of P-Glycoprotein Inhibitors in the Bioavailability Enhancement of Solid Dispersion of Darunavir.
Saleha RehmanBushra NabiMohammad FazilSaba KhanNaimat Kalim BariRomi SinghShavej AhmadVarinder KumarSanjula BabootaJaved AliPublished in: BioMed research international (2017)
It is concluded that SD of DRV with the incorporation of Kolliphor TPGS was potential and promising approach in increasing bioavailability of DRV as well as minimizing its extrusion via P-glycoprotein efflux transporters.