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Alzheimer's disease CSF biomarkers correlate with early pathology and alterations in neuronal and glial gene expression.

Ali S RopriTiffany G LamVrinda KaliaHeather M BuchananAnne Marie W BartoschElliot H H YouthHarrison XiaoSophie K RossAnu JainJayanta K ChakrabartyMin Suk KangDeborah BoyettEleonora F SpinazziGail IodiceRobert A McGovernLawrence S HonigLewis M BrownGary W MillerGuy M McKhannAndrew F Teich
Published in: medRxiv : the preprint server for health sciences (2024)
As additional biomarkers are added to AD diagnostic panels, our work provides insight into the CNS pathophysiology these markers are tracking.
Keyphrases
  • gene expression
  • dna methylation
  • blood brain barrier
  • spinal cord injury
  • cerebral ischemia
  • spinal cord
  • subarachnoid hemorrhage