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Diffuse distribution of tumor-infiltrating lymphocytes is a marker for better prognosis and chemotherapeutic effect in triple-negative breast cancer.

Akira I HidaTakahiro WatanabeYasuaki SagaraMasahiro KashiwabaYoshiaki SagaraKenjiro AogiYasuyo OhiAkihide Tanimoto
Published in: Breast cancer research and treatment (2019)
Showing similar clinical impacts to the TIL density, diffuse TILs could be a predictive marker for better prognosis and higher pCR. The assessment of TIL distribution pattern is simple, faster, and practical. Heterogeneous tumor immunity may contribute to further stratification of TNBC treatment.
Keyphrases
  • low grade
  • peripheral blood
  • high grade