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Hypercholesterolemic Dysregulation of Calpain in Lymphatic Endothelial Cells Interferes With Regulatory T-Cell Stability and Trafficking.

Takuro MiyazakiYoshitaka TaketomiTakayoshi HigashiHirokazu OhtakiTakashi TakakiKoji OhnishiMasahiro HosonumaNozomu KonoRisako AkasuShogo HaraguchiJoo-Ri Kim-KaneyamaKinya OtsuHiroyuki AraiMakoto MurakamiAkira Miyazaki
Published in: Arteriosclerosis, thrombosis, and vascular biology (2022)
Calpain systems in LECs have a key role in controlling Treg stability and trafficking under hypercholesterolemia.
Keyphrases
  • endothelial cells
  • lymph node
  • transcription factor
  • high glucose
  • type diabetes
  • vascular endothelial growth factor