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UM171 suppresses breast cancer progression by inducing KLF2.

Xiaojuan RanAnling HuYi KuangChunlin WangWuling LiuXiao XiaoEldad ZacksenhausXiangdi YuYaacov Ben-David
Published in: Breast cancer research and treatment (2024)
These results suggested that UM171 inhibited breast cancer progression in part through activation of KLF2 and P21. Combination of UM171 with a PAN-PIM inhibitor offer a novel therapy for aggressive forms of breast cancer.
Keyphrases
  • transcription factor
  • signaling pathway
  • breast cancer risk