Characterizing OPRM1 DNA methylation in prescription opioid users with chronic musculoskeletal pain.

Sophia SheikhCarmen SmothermanMonika PatelTaimour LangaeeDanxin WangEdward SwarayEsteban VelasquezSiegfried O F SchmidtPhyllis HendryLarisa H CavallariRoger B Fillingim

Published in: Pain reports (2022)

methylation levels varied by several patient factors. Further studies are warranted to replicate these findings and determine potential clinical utility.

Keyphrases

dna methylation
chronic pain
pain management
genome wide
gene expression
case report
neuropathic pain
case control
human health
copy number
risk assessment
spinal cord
climate change